Title : Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.

Pub. Date : 2018 Jan 24

PMID : 29367637






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKalpha/Smad3 signaling. rosmarinic acid SMAD family member 3 Mus musculus
2 Activated AMPKalpha was essential for the anti-fibrotic effect of RA via inhibiting the phosphorylation and nuclear translocation of Smad3 in vivo and in vitro, and AMPKalpha deficiency abolished RA-mediated protective effects. rosmarinic acid SMAD family member 3 Mus musculus