Pub. Date : 2018 Feb
PMID : 29362093
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A molecular dynamics analysis of the Arg376 > Lys mutation based on the CYP3A4 (a human CYP450) protein structure found that it was responsible for the increase in axis length toward the heme (active site), which is critically important for biological activity and ligand binding. | Lysine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |