Title : [4pp Mucocutaneous manifestations of methotrexate toxicity].

Pub. Date : 2018

PMID : 29360079






1 Functional Relationships(s)
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1 Methotrexate is an antimetabolite analog to folic acid that competitively inhibits the enzyme dihydrofolate reductase and thymidylate synthetase, essential for the synthesis of DNA and RNA. Folic Acid thymidylate synthetase Homo sapiens