Title : COX16 is required for assembly of cytochrome c oxidase in human cells and is involved in copper delivery to COX2.

Pub. Date : 2018 Apr

PMID : 29355485






2 Functional Relationships(s)
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1 COX16 is required for assembly of cytochrome c oxidase in human cells and is involved in copper delivery to COX2. Copper mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Finally, we found that copper supplementation increases COX activity and restores normal steady state levels of COX subunits in COX16 knockout cells, indicating that, even in the absence of a canonical copper binding motif, COX16 could be involved in copper delivery to COX2. Copper mitochondrially encoded cytochrome c oxidase II Homo sapiens