Title : The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy.

Pub. Date : 2017 Dec 19

PMID : 29340025






1 Functional Relationships(s)
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Protein Name
Organism
1 Treatment with irinotecan significantly elevated the ATM pathway evident by an increase in the activation of H2AX and RAD50. Irinotecan RAD50 double strand break repair protein Homo sapiens