Title : Physiological based pharmacokinetic modeling to estimate in vivo Ki of ketoconazole on renal P-gp using human drug-drug interaction study result of fesoterodine and ketoconazole.

Pub. Date : 2018 Feb

PMID : 29338933






1 Functional Relationships(s)
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Protein Name
Organism
1 Fesoterodine is a prodrug which is extensively hydrolyzed by non-specific esterases to the active metabolite 5-hydroxymethyl tolterodine (5-HMT). fesoterodine histamine N-methyltransferase Homo sapiens