Title : Behavior of C-reactive protein in association with surgery of facial fracture and the influence of dexamethasone.

Pub. Date : 2018 Jun

PMID : 29335791






6 Functional Relationships(s)
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1 PURPOSE: To clarify pre- and postoperative C-reactive protein (CRP) levels in patients with facial fractures and to investigate the influence of perioperatively administered dexamethasone on postoperative CRP levels. Dexamethasone C-reactive protein Homo sapiens
2 However, postoperative CRP rise was significantly impeded by dexamethasone (p < 0.001), regardless of gender, age, treatment delay, site of fracture, surgical approach, and duration of surgery. Dexamethasone C-reactive protein Homo sapiens
3 CRP rise halved on the 1st postoperative day when dexamethasone was used. Dexamethasone C-reactive protein Homo sapiens
4 In addition, dexamethasone resulted in a CRP decrease on the 2nd postoperative day, whereas the CRP rise continued in the control group. Dexamethasone C-reactive protein Homo sapiens
5 CONCLUSIONS: CRP rise is a normal body response after facial fracture and surgery that can be markedly reduced with dexamethasone. Dexamethasone C-reactive protein Homo sapiens
6 CRP changes should be considered with caution if perioperative dexamethasone is used. Dexamethasone C-reactive protein Homo sapiens