Title : APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models.

Pub. Date : 2018 Apr

PMID : 29331876






1 Functional Relationships(s)
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1 Gallein, a selective pharmacological inhibitor of Gbetagamma complex, inhibited Abeta-induced dendritic and axonal dystrophy, abnormal tau phosphorylation, synaptic loss, and neuronal cell death in hippocampal neurons expressing endogenous protein levels. gbetagamma amyloid beta (A4) precursor protein Mus musculus