Pub. Date : 2017 Dec
PMID : 29319721
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Microcirculation improvement after short-term infusion of vasopressin in septic shock is dependent on noradrenaline. | Norepinephrine | arginine vasopressin | Homo sapiens |
2 | The noradrenaline dose was significantly reduced after vasopressin (p=0.001) and was higher both at baseline and during vasopressin infusion in the responders than in the non-responders. | Norepinephrine | arginine vasopressin | Homo sapiens |
3 | The noradrenaline dose was significantly reduced after vasopressin (p=0.001) and was higher both at baseline and during vasopressin infusion in the responders than in the non-responders. | Norepinephrine | arginine vasopressin | Homo sapiens |
4 | For patients using a noradrenaline dose higher than 0.38 mcg/kg/min, the probability that microcirculatory perfusion would be improved with vasopressin was 53% (sensitivity 78%, specificity 77%). | Norepinephrine | arginine vasopressin | Homo sapiens |
5 | CONCLUSIONS: In patients with septic shock for no longer than 48 h, administration of vasopressin is likely to result in an improvement in microcirculation when the baseline noradrenaline dose is higher than 0.38 mcg/kg/min. | Norepinephrine | arginine vasopressin | Homo sapiens |