Title : Assessment of drug-drug interaction potential and PBPK modeling of CC-223, a potent inhibitor of the mammalian target of rapamycin kinase.

Pub. Date : 2019 Jan

PMID : 29297772






1 Functional Relationships(s)
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1 Model based predictions of DDI with ketoconazole were in agreement with observed results enabling prospective predictions of DDIs between CC-223 and CYP3A4 inhibitors. Ketoconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens