Pub. Date : 2017 May 9
PMID : 29296720
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. | Tranexamic Acid | plasminogen | Homo sapiens |
| 2 | Currently, tranexamic acid (TXA), a molecule that prevents plasminogen activation through blocking recruitment to target substrates, is the most widely used inhibitor for the plasminogen/plasmin system in therapeutics. | Tranexamic Acid | plasminogen | Homo sapiens |
| 3 | Currently, tranexamic acid (TXA), a molecule that prevents plasminogen activation through blocking recruitment to target substrates, is the most widely used inhibitor for the plasminogen/plasmin system in therapeutics. | Tranexamic Acid | plasminogen | Homo sapiens |
| 4 | Here, the TXA moiety of the YO compounds inserts into the primary (S1) specificity pocket, suggesting that TXA itself may function as a weak plasmin inhibitor, a hypothesis supported by subsequent biochemical and biophysical analyses. | Tranexamic Acid | plasminogen | Homo sapiens |
| 5 | Here, the TXA moiety of the YO compounds inserts into the primary (S1) specificity pocket, suggesting that TXA itself may function as a weak plasmin inhibitor, a hypothesis supported by subsequent biochemical and biophysical analyses. | Tranexamic Acid | plasminogen | Homo sapiens |