Title : Suppressive effects of capsaicin against N-nitrosomethylurea-induced mammary tumorigenesis in rats.

Pub. Date : 2018 Feb

PMID : 29294454






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Additionally, the NMU exposure and capsaicin treated group significantly showed the protective potential of capsaicin in restoring the altered sexual hormones, antioxidants and other biochemical analyses. Capsaicin neuromedin U Rattus norvegicus
2 Rats treated with NMU and protected with capsaicin improved the histopathological changes induced by NMU and showed that the desquamation of most of the layers of carcinoma cells leaving one or two epithelial layers in some cases and in some instances. Capsaicin neuromedin U Rattus norvegicus
3 Animals treated with NMU immunostained for PCNA displayed the strong positive stained nuclei in most of the cells, but in capsaicin treated against the NMU effects immunostained for PCNA displayed that the positive stained nuclei was less than that detected in NMU group. Capsaicin neuromedin U Rattus norvegicus
4 Animals treated with NMU immunostained for PCNA displayed the strong positive stained nuclei in most of the cells, but in capsaicin treated against the NMU effects immunostained for PCNA displayed that the positive stained nuclei was less than that detected in NMU group. Capsaicin neuromedin U Rattus norvegicus
5 Animals treated with NMU immunostained for PCNA displayed the strong positive stained nuclei in most of the cells, but in capsaicin treated against the NMU effects immunostained for PCNA displayed that the positive stained nuclei was less than that detected in NMU group. Capsaicin neuromedin U Rattus norvegicus
6 To conclude, the results have clearly shown that capsaicin performs a very important defensive role during breast carcinogenesis and has the ability to act as a chemo-suppressive factor against NMU effects. Capsaicin neuromedin U Rattus norvegicus