Title : Nitrogen-containing ecdysteroid derivatives vs. multi-drug resistance in cancer: Preparation and antitumor activity of oximes, oxime ethers and a lactam.

Pub. Date : 2018 Jan 20

PMID : 29291440






2 Functional Relationships(s)
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Protein Name
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1 Oxime and particularly oxime ether formation strongly increased their inhibitory activity on the efflux of rhodamine 123 by P-glycoprotein (P-gp), while the new ecdysteroid lactam did not interfere with the efflux function. Rhodamines ATP binding cassette subfamily B member 1 Homo sapiens
2 Oxime and particularly oxime ether formation strongly increased their inhibitory activity on the efflux of rhodamine 123 by P-glycoprotein (P-gp), while the new ecdysteroid lactam did not interfere with the efflux function. Rhodamines ATP binding cassette subfamily B member 1 Homo sapiens