Title : Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception.

Pub. Date : 2018 Mar 8

PMID : 29291372






1 Functional Relationships(s)
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1 With the goal of discovering selective inhibitors of the Na,K-ATPase alpha4 and of sperm function, ouabain derivatives were modified at the glycone (C3) and the lactone (C17) domains. Lactones cytokine-like 1 Mus musculus