Pub. Date : 2018 Mar 1
PMID : 29288081
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We describe the development of a nanoparticulate system, with variation of poly(ethylene glycol) (PEG) content, capable of releasing therapeutic levels of bioactive insulin for extended periods of time. | Polyethylene Glycols | insulin | Homo sapiens |
2 | We describe the development of a nanoparticulate system, with variation of poly(ethylene glycol) (PEG) content, capable of releasing therapeutic levels of bioactive insulin for extended periods of time. | Polyethylene Glycols | insulin | Homo sapiens |
3 | Recombinant human insulin was encapsulated in poly(d,l-lactide-co-glycolide) nanoparticles, manufactured with variation in poly(ethylene glycol) content, and shown to be stable for 6days using SDS-PAGE, western blot and MALDI MS. To determine if insulin released from this sustained release matrix could stimulate migration of cell types normally active in dermal repair, a model wound was simulated by scratching confluent cultures of human keratinocytes (HaCaT) and fibroblasts (Hs27). | Polyethylene Glycols | insulin | Homo sapiens |