Title : The translesion DNA polymerases Pol ζ and Rev1 are activated independently of PCNA ubiquitination upon UV radiation in mutants of DNA polymerase δ.

Pub. Date : 2017 Dec

PMID : 29281621






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In eukaryotes, Rad6- and Rad18-mediated PCNA ubiquitination at lysine 164 promotes recruitment of TLS polymerases, allowing cells to efficiently cope with DNA damage. Lysine E3 ubiquitin-protein ligase RAD18 Saccharomyces cerevisiae S288C