Title : Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer.

Pub. Date : 2018 Mar

PMID : 29233910






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 BRAFV600E colorectal cancer cell lines expressing CDK1 were sensitized to apoptosis upon siRNA knockdown or small-molecule inhibition with RO-3306 (CDK1 inhibitor) or dinaciclib (CDK1, 2, 5, 9 inhibitors). dinaciclib cyclin dependent kinase 1 Homo sapiens