Title : Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase.

Pub. Date : 2018 Jan 15

PMID : 29233683






1 Functional Relationships(s)
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1 This XRCC4-dependent, SRPK1/SRSF1-mediated regulatory mechanism was conserved in apoptosis in Jurkat human leukemia cells triggered by STS, and by two widely used anti-cancer agents, Paclitaxel and Vincristine. Paclitaxel X-ray repair cross complementing 4 Homo sapiens