Title : Autophagy inhibition sensitizes LY3023414-induced anti-glioma cell activity in vitro and in vivo.

Pub. Date : 2017 Nov 17

PMID : 29228741






3 Functional Relationships(s)
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Protein Name
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1 LY3023414 is a novel, highly-potent and pan PI3K-AKT-mTOR inhibitor. LY3023414 AKT serine/threonine kinase 1 Homo sapiens
2 LY3023414 blocked AKT-mTOR activation in human glioma cells. LY3023414 AKT serine/threonine kinase 1 Homo sapiens
3 Together, our results suggest that targeting PI3K-AKT-mTOR cascade by LY3023414 inhibits human glioma cell growth in vitro and in vivo. LY3023414 AKT serine/threonine kinase 1 Homo sapiens