Title : Autophagy inhibition sensitizes LY3023414-induced anti-glioma cell activity in vitro and in vivo.

Pub. Date : 2017 Nov 17

PMID : 29228741






2 Functional Relationships(s)
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1 On the other hand, autophagy inhibition via adding pharmacological inhibitors or silencing Beclin-1/ATG-5 significantly potentiated LY3023414-induced glioma cell apoptosis. LY3023414 beclin 1 Homo sapiens
2 Remarkably, LY3023414"s anti-tumor activity was further augmented against the Beclin-1-silenced U251MG tumors. LY3023414 beclin 1 Homo sapiens