Title : Long intergenic non‑coding RNA‑p21 mediates cardiac senescence via the Wnt/β‑catenin signaling pathway in doxorubicin-induced cardiotoxicity.

Pub. Date : 2018 Feb

PMID : 29207090






1 Functional Relationships(s)
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1 Dox-induced cardiac senescence was accompanied by decreased cellular proliferation and viability, increased expression of p53 and p16, and decreased telomere length and telomerase activity, while these effects were relieved by silencing endogenous lincRNA-p21. Doxorubicin tumor protein p53 Homo sapiens