Title : Tan IIA inhibits H1299 cell viability through the MDM4‑IAP3 signaling pathway.

Pub. Date : 2018 Feb

PMID : 29207086






2 Functional Relationships(s)
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1 Notably, a combination of Tan IIA and doxorubicin (DOX) exposure resulted in further MDM4 overexpression in H1299 cells, indicating that Tan IIA sensitized p53-deficient and MDM4-overexpressing H1299 cells to DOX-induced apoptosis. Doxorubicin tumor protein p53 Homo sapiens
2 Notably, a combination of Tan IIA and doxorubicin (DOX) exposure resulted in further MDM4 overexpression in H1299 cells, indicating that Tan IIA sensitized p53-deficient and MDM4-overexpressing H1299 cells to DOX-induced apoptosis. Doxorubicin tumor protein p53 Homo sapiens