Title : Anti-inflammatory effect of lovastatin is mediated via the modulation of NF-κB and inhibition of HDAC1 and the PI3K/Akt/mTOR pathway in RAW264.7 macrophages.

Pub. Date : 2018 Feb

PMID : 29207042






1 Functional Relationships(s)
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1 Furthermore, the expression of phosphoinositide 3-kinase catalytic subunits alpha and beta was reduced under lovastatin treatment, and the phosphorylation of Akt and mammalian target of rapamycin was consequently inhibited. Lovastatin AKT serine/threonine kinase 1 Homo sapiens