Title : In contrast to morphine, buprenorphine enhances macrophage-induced humoral immunity and, as oxycodone, slightly suppresses the effector phase of cell-mediated immune response in mice.

Pub. Date : 2018 Jan

PMID : 29197801






1 Functional Relationships(s)
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1 The enhanced generation of reactive oxygen intermediates and nitric oxide by macrophages from mice treated with buprenorphine, oxycodone or morphine was also shown, along with increased release of IL-6, TNFalpha and TGFbeta. Buprenorphine interleukin 6 Mus musculus