Title : Hypothesis: Hypoxia induces de novo synthesis of NeuGc gangliosides in humans through CMAH domain substitute.

Pub. Date : 2018 Jan 1

PMID : 29196263






1 Functional Relationships(s)
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1 Here, we confirm hypoxia-induced expression of the NeuGc GM3 ganglioside also in HeLa cells and reveal several candidate proteins, in particular GM3 synthase and subunit B of respiratory complex II (SDHB), that may be involved in the generation of NeuGc GM3 by SILAC-based proteome analysis. G(M3) Ganglioside succinate dehydrogenase complex iron sulfur subunit B Homo sapiens