Title : Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells.

Pub. Date : 2017 Dec

PMID : 29174536






2 Functional Relationships(s)
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Protein Name
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1 Decitabine (DAC), a nucleoside-related DNA methylation inhibitor, is taken up into cancer cells via equilibrative nucleoside transporter 1 (ENT1), and is then monophosphorylated by deoxycytidine kinase (dCK). Decitabine solute carrier family 29 member 1 (Augustine blood group) Homo sapiens
2 Decitabine (DAC), a nucleoside-related DNA methylation inhibitor, is taken up into cancer cells via equilibrative nucleoside transporter 1 (ENT1), and is then monophosphorylated by deoxycytidine kinase (dCK). Decitabine solute carrier family 29 member 1 (Augustine blood group) Homo sapiens