Title : Long non-coding RNA LUCAT1 modulates methotrexate resistance in osteosarcoma via miR-200c/ABCB1 axis.

Pub. Date : 2018 Jan 1

PMID : 29170124






2 Functional Relationships(s)
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Protein Name
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1 LncRNA LUCAT1 and ABCB1 protein expression levels were both up-regulated when induced by different concentration of methotrexate. Methotrexate ATP binding cassette subfamily B member 1 Homo sapiens
2 Overall, results indicate the vital role of LUCAT1 in the methotrexate resistance regulation through miR-200c/ABCB1 pathway, providing a novel insight and treatment strategy for osteosarcoma drug resistance. Methotrexate ATP binding cassette subfamily B member 1 Homo sapiens