Title : The thymidylate synthase enhancer region (TSER) polymorphism increases the risk of thymic lymphoid hyperplasia in patients with Myasthenia Gravis.

Pub. Date : 2018 Feb 5

PMID : 29162511






2 Functional Relationships(s)
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1 METHODS: We investigated if major polymorphisms of folate-related genes, namely MTHFR c.677C>T, MTR c.2756A>G, MTRR c.66A>G and TYMS TSER (a 28-bp tandem repeat in the 5" promoter enhancer region of TYMS) increase the risk of pathological changes of the thymus in AChR+ MG patients. Folic Acid thymidylate synthetase Homo sapiens
2 METHODS: We investigated if major polymorphisms of folate-related genes, namely MTHFR c.677C>T, MTR c.2756A>G, MTRR c.66A>G and TYMS TSER (a 28-bp tandem repeat in the 5" promoter enhancer region of TYMS) increase the risk of pathological changes of the thymus in AChR+ MG patients. Folic Acid thymidylate synthetase Homo sapiens