Title : Asiatic acid protects against hepatic ischemia/reperfusion injury by inactivation of Kupffer cells via PPARγ/NLRP3 inflammasome signaling pathway.

Pub. Date : 2017 Oct 17

PMID : 29156799






1 Functional Relationships(s)
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1 Mechanistically, AA attenuated I/R or LPS/H2O2-induced ROS production and phosphorylation level of JNK, p38 MAPK and IkappaBalpha but not ERK, a mechanism dependent on PPARgamma. Hydrogen Peroxide nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus