Pub. Date : 2017 Oct 17
PMID : 29156686
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AGS cells over-expressing Polbeta were resistant to 6-TG to a similar extent as when MLH1 was inactivated while inhibition of O6-methylguanine-DNA methyltransferase (MGMT) was required to detect resistance to MMS. | Methyl Methanesulfonate | DNA polymerase beta | Homo sapiens |
| 2 | Moreover, AGS cells mutated in Polbeta were hypersensitive to both 6-TG and MMS killing and their sensitivity was partially rescued by MLH1 silencing. | Methyl Methanesulfonate | DNA polymerase beta | Homo sapiens |