Pub. Date : 2017 Oct 20
PMID : 29152112
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, the present study demonstrated that sorafenib treatment induces activation of Akt, probably as a mechanism of resistance, whereas capsaicin inhibits Akt providing a possible pathway whereby capsaicin sensitizes to sorafenib in HCC cells. | Capsaicin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Knocking down of AMPK by selective siRNA abrogates capsaicin-induced Akt inhibition, suggesting the involvement of AMPK in the antiproliferative effect. | Capsaicin | AKT serine/threonine kinase 1 | Homo sapiens |