Title : Propoxur enhances MMP-2 expression and the corresponding invasion of human breast cancer cells via the ERK/Nrf2 signaling pathway.

Pub. Date : 2017 Oct 20

PMID : 29152067






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 PD98059, a MEK inhibitor, was administered to block the ERK/MAPK pathway. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen-activated protein kinase 3 Homo sapiens
2 Inversely, inhibition of ERK1/2 activation with PD98059 significantly attenuated propoxur-induced Nrf2 expression and nuclear translocation. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen-activated protein kinase 3 Homo sapiens