Title : Stimulus-response click chemistry based aptamer-functionalized mesoporous silica nanoparticles for fluorescence detection of thrombin.

Pub. Date : 2018 Feb 1

PMID : 29136862






2 Functional Relationships(s)
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1 Upon the introduction of thrombin, thrombin specifically recognized its aptamer, so aptamer released from the MSN; and the single strand DNA(ssDNA) left could not cap the pores of the MSN efficiently and hence caused the releasing of fluorescein into the solution. Fluorescein coagulation factor II, thrombin Homo sapiens
2 Upon the introduction of thrombin, thrombin specifically recognized its aptamer, so aptamer released from the MSN; and the single strand DNA(ssDNA) left could not cap the pores of the MSN efficiently and hence caused the releasing of fluorescein into the solution. Fluorescein coagulation factor II, thrombin Homo sapiens