Title : The Effects of Magnesium and Zinc Co-Supplementation on Biomarkers of Inflammation and Oxidative Stress, and Gene Expression Related to Inflammation in Polycystic Ovary Syndrome: a Randomized Controlled Clinical Trial.

Pub. Date : 2018 Aug

PMID : 29127547






3 Functional Relationships(s)
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1 Results of RT-PCR demonstrated that compared with the placebo, magnesium and zinc co-supplementation downregulated gene expression of interleukin-1 (IL-1) (P = 0.007) and tumor necrosis factor alpha (TNF-alpha) (P = 0.03) in PBMCs of subjects with PCOS. Magnesium tumor necrosis factor Homo sapiens
2 Results of RT-PCR demonstrated that compared with the placebo, magnesium and zinc co-supplementation downregulated gene expression of interleukin-1 (IL-1) (P = 0.007) and tumor necrosis factor alpha (TNF-alpha) (P = 0.03) in PBMCs of subjects with PCOS. Magnesium tumor necrosis factor Homo sapiens
3 Overall, magnesium and zinc co-supplementation, compared with the placebo, for 12 weeks among PCOS women had beneficial effects on serum hs-CRP, plasma PCO, TAC, and gene expression of IL-1 and TNF-alpha. Magnesium tumor necrosis factor Homo sapiens