Title : Tetracyclines downregulate the production of LPS-induced cytokines and chemokines in THP-1 cells via ERK, p38, and nuclear factor-κB signaling pathways.

Pub. Date : 2015 Dec

PMID : 29124230






1 Functional Relationships(s)
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1 In addition, SB203580 (p38 inhibitor) and U0126 (ERK1/2 inhibitor) significantly suppressed the expression of TNF-alpha and IL-8 in LPS-stimulated THP-1 cells. SB 203580 mitogen-activated protein kinase 1 Homo sapiens