Pub. Date : 2017 Dec 1
PMID : 29122484
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Delphinidin inhibits BDNF-induced migration and invasion in SKOV3 ovarian cancer cells. | delphinidin | brain derived neurotrophic factor | Homo sapiens |
| 2 | Here, we found that delphinidin prominently inhibited the BDNF-induced increase in cell migration and invasion of SKOV3 ovarian cancer cells. | delphinidin | brain derived neurotrophic factor | Homo sapiens |
| 3 | Furthermore, delphinidin remarkably inhibited BDNF-stimulated expression of MMP-2 and MMP-9. | delphinidin | brain derived neurotrophic factor | Homo sapiens |
| 4 | Also, delphinidin antagonized the phosphorylation of Akt and nuclear translocation of NF-kappaB permitted by the BDNF in SKOV3 ovarian cancer cells. | delphinidin | brain derived neurotrophic factor | Homo sapiens |
| 5 | Taken together, our findings provide new evidence that delphinidin suppressed the BDNF-induced ovarian cancer migration and invasion through decreasing of Akt activation. | delphinidin | brain derived neurotrophic factor | Homo sapiens |