Pub. Date : 2018 Jan 17
PMID : 29120942
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quetiapine prevents Abeta25-35-induced cell death in cultured neuron by enhancing brain-derived neurotrophic factor release from astrocyte. | Quetiapine Fumarate | brain derived neurotrophic factor | Homo sapiens |
| 2 | Furthermore, we revealed that QTP increased both the release of brain-derived neurotrophic factor from cultured astrocytes and the phosphorylation of extracellular signal-regulated kinase after 24 h of treatment, which might be responsible for its protective effects on neurons. | Quetiapine Fumarate | brain derived neurotrophic factor | Homo sapiens |
| 3 | In conclusion, our data demonstrated that QTP exerted its neuroprotective effects against amyloid toxicity by enhancing the brain-derived neurotrophic factor release from astrocytes. | Quetiapine Fumarate | brain derived neurotrophic factor | Homo sapiens |