Pub. Date : 2019 Mar
PMID : 29120670
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Correlation Between Steroid-Induced Osteonecrosis of The Femoral Head and Hepatic CYP3A Activity: A Systematic Review and Meta-Analysis. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
2 | This study aims to review the investigations on the hepatic CYP3A (cytochrome P4503A enzyme) genetic polymorphisms in steroid-induced ONFH patients. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
3 | This study aims to review the investigations on the hepatic CYP3A (cytochrome P4503A enzyme) genetic polymorphisms in steroid-induced ONFH patients. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
4 | The odds ratios, standard mean difference, and 95% confidence intervals were calculated to assess the effect of hepatic CYP3A activity on the rabbit model with steroid-induced ONFH. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
5 | RESULTS: High hepatic CYP3A activity significantly decreased the risk for steroid-induced ONFH in the rabbit model (p <. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
6 | The CYP3A gene may be potentially associated with increased risk of steroid-induced ONFH in the human allele model. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
7 | CONCLUSION: The study suggests that high hepatic CYP3A activity decreases the risk of steroid-induced ONFH. | Steroids | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |