Pub. Date : 2017 Oct 6
PMID : 29113387
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Meanwhile, the dose of FK506 and CsA was recorded, blood concentration of the drugs was measured, and graft outcome was monitored.These results indicate that CYP3A5*AA/AG carriers need higher FK506 dose than CYP3A5*GG homozygote to achieve the target blood concentration. | Cyclosporine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |
| 2 | For CYP3A5*GG carriers, taking FK506 or CsA are both advisable. | Cyclosporine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |
| 3 | CYP3A5 genotyping is a new approach to detecting FK506 dose requirement and a predictive index for the FK506 or CsA treatment selection in kidney recipients. | Cyclosporine | cytochrome P450 family 3 subfamily A member 5 | Homo sapiens |