Title : Calycosin inhibits the in vitro and in vivo growth of breast cancer cells through WDR7-7-GPR30 Signaling.

Pub. Date : 2017 Nov 2

PMID : 29096683






1 Functional Relationships(s)
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1 Additionally, in all four GPR30-positive breast cancer lines, calycosin decreased the phosphorylation levels of SRC, EGFR, ERK1/2 and Akt, but the inhibition of WDR7-7 blocked these changes and increased proliferation. 7,3'-dihydroxy-4'-methoxyisoflavone AKT serine/threonine kinase 1 Homo sapiens