Title : [3H]8-OH-DPAT labels the 5-hydroxytryptamine uptake recognition site and the 5-HT1A binding site in the rat striatum.

Pub. Date : 1988 Dec

PMID : 2907586






3 Functional Relationships(s)
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1 Thus [3H]8-OH-DPAT labels the 5-HT transporter in the rat striatum. 8-Hydroxy-2-(di-n-propylamino)tetralin solute carrier family 6 member 4 Rattus norvegicus
2 Unlike [3H]imipramine binding, the binding of [3H]8-OH-DPAT to the 5-HT transporter was independent of external sodium ions. 8-Hydroxy-2-(di-n-propylamino)tetralin solute carrier family 6 member 4 Rattus norvegicus
3 It is therefore suggested that 8-OH-DPAT acts as substrate for the 5-HT transporter and labels the 5-HT recognition site of the transporter complex. 8-Hydroxy-2-(di-n-propylamino)tetralin solute carrier family 6 member 4 Rattus norvegicus