Title : [Effect of BBG on Acute Graft-Versus-Host Disease in Mice after Allogeneic Hematopoietic Stem Cell Transplantation].

Pub. Date : 2017 Oct

PMID : 29070142






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1 RESULTS: The allo-HSCT aGVHD mouse model was successfully established, the intraperitoneal injection of BBG alleviated the aGVHD clinical manifestations including roachback, ruffled fur, skin peeling and weight loss of recipient mice, decreased P2X7R and IL-1beta expression and reduced the mRNA levels of P2X7R, NLRP3, Caspase-1, IL-1beta and IL-18. coomassie Brilliant Blue NLR family, pyrin domain containing 3 Mus musculus