Pub. Date : 2017
PMID : 29066864
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The pharmacodynamic analysis revealed that the maximum effect of COX-2 inhibition was achieved at 2.0 hours for all genotypes of COX-2 SNPs after a single oral administration of 200 mg celecoxib. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | The pharmacodynamic analysis revealed that the maximum effect of COX-2 inhibition was achieved at 2.0 hours for all genotypes of COX-2 SNPs after a single oral administration of 200 mg celecoxib. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 3 | CONCLUSION: Our results demonstrated that inhibitory effects of celecoxib on COX-2 induction were different according to the genotype of COX-2 SNPs. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 4 | CONCLUSION: Our results demonstrated that inhibitory effects of celecoxib on COX-2 induction were different according to the genotype of COX-2 SNPs. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 5 | In the present study, rs689466 is responsible for the variability of the response to celecoxib, suggesting that a subject with the GG genotype of rs689466 would be more responsive to celecoxib in terms of COX-2 inhibition. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 6 | In the present study, rs689466 is responsible for the variability of the response to celecoxib, suggesting that a subject with the GG genotype of rs689466 would be more responsive to celecoxib in terms of COX-2 inhibition. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |