Pub. Date : 2017 Nov - Dec
PMID : 29066094
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | OBJECTIVE: The aim of this work was to study the prevalence of ABCG5/G8 genetic variants in mutation-negative FH, as defects in these genes relate to intestinal hyperabsorption of cholesterol and thus ABCG5/G8 variants could explain in part the mechanism of hypercholesterolemia. | Cholesterol | ATP binding cassette subfamily G member 5 | Homo sapiens |
| 2 | In addition, we found significantly higher concentrations of cholesterol absorption markers in mutation-negative FH with ABCG5/G8 defects than in mutation-negative, ABCG5/G8-negative FH. | Cholesterol | ATP binding cassette subfamily G member 5 | Homo sapiens |