Title : Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-κB signaling in lens epithelial cells.

Pub. Date : 2018 Jan

PMID : 29051011






1 Functional Relationships(s)
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1 These findings suggest that low concentrations of CO protect LECs from H2O2-induced oxidative damage by attenuating NF-kappaB p65 nuclear translocation, reducing the generation of ROS and apoptotic molecules, and restoring antioxidant enzyme levels, thereby inhibiting LECs apoptosis. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens