Title : Transforming Mutations of Jak3 (A573V and M511I) Show Differential Sensitivity to Selective Jak3 Inhibitors.

Pub. Date : 2016

PMID : 29046866






2 Functional Relationships(s)
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1 CONCLUSION: Jak3 inhibitors CP-690,550 and NC1153 showed efficacy in reducing viability of Ba/F3 cells transformed with mutant forms of Jak3, thus providing new therapeutic strategies to treat these types of cancer. tofacitinib Janus kinase 3 Mus musculus
2 CONCLUSION: Jak3 inhibitors CP-690,550 and NC1153 showed efficacy in reducing viability of Ba/F3 cells transformed with mutant forms of Jak3, thus providing new therapeutic strategies to treat these types of cancer. tofacitinib Janus kinase 3 Mus musculus