Title : Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression.

Pub. Date : 2017

PMID : 29045468






2 Functional Relationships(s)
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1 Specifically, cordycepin inhibited TNF-alpha-mediated NF-kappaB activation, which induced renal cancer cell apoptosis. cordycepin nuclear factor kappa B subunit 1 Homo sapiens
2 Taken together, the results indicate that cordycepin inhibits TNF-alpha-mediated NF-kappaB/GADD45B signaling, which activates the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression, thus inducing TK-10 cell apoptosis. cordycepin nuclear factor kappa B subunit 1 Homo sapiens