Title : Mouse hepatic cytochrome P-450 isozyme induction by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene, pyrazole, and phenobarbital.

Pub. Date : 1988 Nov 1

PMID : 2903743






1 Functional Relationships(s)
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1 In immunoblot experiments with anti-P-450Coh antibody, the amount of P-450Coh was considerably higher in DBA/2N mice treated with phenobarbital, TCPOBOP, or pyrazole in comparison with the AKR/J mice, indicating a strain specificity in the inducibility of coumarin 7-hydroxylase by pyrazole. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus