Title : Distinct deposition of amyloid-β species in brains with Alzheimer's disease pathology visualized with MALDI imaging mass spectrometry.

Pub. Date : 2017 Oct 16

PMID : 29037261






1 Functional Relationships(s)
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1 With technical advancements such as formic acid pretreatment of frozen autopsied brain samples, we have: i) demonstrated that Abeta1-42 and Abeta1-43 were selectively deposited in senile plaques while full-length Abeta peptides such as Abeta1-36, 1-37, 1-38, 1-39, 1-40, and Abeta1-41 were deposited in leptomeningeal blood vessels. formic acid amyloid beta precursor protein Homo sapiens