Pub. Date : 2017 Oct 19
PMID : 29033319
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In rad53-1 cells stressed by dNTP depletion, the replicative DNA helicase, MCM, and the leading-strand DNA polymerase, Pol epsilon, move beyond the site of DNA synthesis, likely unwinding template DNA. | Parathion | checkpoint kinase 2 | Homo sapiens |
| 2 | The asymmetric DNA synthesis in rad53-1 cells is suppressed by elevated levels of dNTPs in vivo, and the activity of Pol epsilon is compromised more than lagging-strand polymerase Pol delta at low dNTP concentrations in vitro. | Parathion | checkpoint kinase 2 | Homo sapiens |
| 3 | The asymmetric DNA synthesis in rad53-1 cells is suppressed by elevated levels of dNTPs in vivo, and the activity of Pol epsilon is compromised more than lagging-strand polymerase Pol delta at low dNTP concentrations in vitro. | Parathion | checkpoint kinase 2 | Homo sapiens |